Ammonium Hydroxide Poisoning is caused by the ingestion, inhalation, or exposure of skin to ammonium hydroxide and ammonium hydroxide based products; This intake could be accidental, or in some cases intentional, to bring self-harm; Ammonium hydroxide is a toxic substance that is found in a variety of cleaning solutions, cosmetics, and cements (USCG, 1999) Reactivity Profile. May cause irritation of the digestive tract. Sore throat. Enter a drug name and ammonium chloride. May cause irritation of the digestive tract. 1.1. On ingestion: Rinse mouth immediately and then drink plenty of water, seek medical attention. Question: - Ammonium Chloride Injection Contains 267.5 Mg Of Nh4cl (m.w. Benzalkonium chloride has repeatedly demonstrated its toxic characteristics in laboratory, experimental, and clinical studies. Effects of ammonium chloride ingestion on phosphocreatine metabolism during moderate- and heavy-intensity plantar-flexion exercise | springermedizin.de Skip to main content It is mainly used as fertilizer and a flavouring agent in some types of liquorice. Ammonia alone (not ammonium hydroxide) can be found in many household items such as detergents, stain removers, bleaches, and dyes. In a dermal sensitization study with ammonium chloride (99.1% pure), 8 weeks old guinea pigs [Pirbright-White (Hoe: DHPK (SPFLac))] were tested according to EPA 540/9-82-025 (November 1982, revised at November 1984), a method comparable to OECD TG 406 (Hoechst, 1986). EXPOSURE: Exposure to didecyl dimethyl ammonium chloride is most often from skin or eye contact, but can also include inhalation or ingestion. Chloride content— Transfer an accurately measured volume of Injection, evaporated, if necessary, equivalent to about 2 g of ammonium chloride, to a 200-mL volumetric flask, dilute with water to volume, and mix. May cause systemic toxicity with acidosis. Test guideline Qualifier: equivalent or similar to Guideline: OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test) Deviations: yes Remarks: (reduced reporting, only 1000 PCE scored for … May be harmful if inhaled. We present a case of an intentional ingestion of a dilute ammonium chloride solution resulting in significant morbidity. Other products may also contain ammonium hydroxide and ammonia. In case of fire in the surroundings, use appropriate extinguishing media. Elliott WC, Parker RA, Houghton DC, Gilbert DN, Porter GA, DeFehr J, Bennett WM. Product form : Substance Substance name : Ammonium Chloride CAS-No. If you take diphenhydramine and ammonium chloride on a regular basis, take a missed dose as soon as you think about it. SYMPTOMS PREVENTION FIRST AID; Inhalation: Cough. AMMONIUM CHLORIDE: ICSC: 1051: Sal ammoniac: December 2000: CAS #: 12125-02-9 EC Number: 235-186-4 ACUTE HAZARDS PREVENTION FIRE FIGHTING; FIRE & EXPLOSION: Not combustible. Ammonium Chloride has no known severe interactions with other drugs. Identification . Case Report. Ingestion: Rinse mouth. Ingestion of the chemical could result in serious negative health consequences, including death. Many times diphenhydramine and ammonium chloride is taken on an as needed basis. They react as acids to neutralize bases. Chloride content— Transfer an accurately measured volume of Injection,evaporated,if necessary,equivalent to about 2g of ammonium chloride,to a 200-mLvolumetric flask,dilute with water to volume,and mix.Transfer 10.0mLof this solution to a conical flask,add 10mLof glacial acetic acid,75mLof methanol,and 0.5mLof eosin Y TS.Titrate,with shaking,with 0.1Nsilver nitrate VSto a pink … Moderate interactions of ammonium chloride include: amphetamine; dextroamphetamine; dichlorphenamide; lisdexamfetamine; methamphetamine; methylenedioxymethamphetamine; Mild interactions of ammonium chloride include: spironolactone ; This document does not contain all possible interactions. Inhalation: If heated, dust or fume may cause respiratory tract irritation. 77, No. It is a antimicrobial agent, deodorant, surfactant, and a preservative. The symptoms and treatment for ammonia exposure are similar to those for ammonium hydroxide. Ammonium Chloride Salmiac 12125-02-9 NH 4Cl ≥ 99.5 Trade Secret Statement: Not applicable. How Many Meq Of Ammonium Chloride Are Present In A 20-ml Vial ?-apatient Is Given 125mg Phenytoin Sodium(c15h11n2nao2—m.w.274)three Times A Day. If breathing is difficult, give oxygen. It should be used with caution in patients with high total CO2 and buffer base secondary to primary respiratory acidosis. 53.5) Per Milliliter. Next: Interactions. Contact with eyes or skin causes irritation. Ingestion of ammonia does not normally result in systemic poisoning. Benzalkonium chloride itself is a mixture of very similar substances with different chain length and molecular mass. It is an irritant of the skin, eyes, mucous membranes, and upper respiratory tract. Ammonium Chloride Ingestion Attenuates Exercise-Induced mRNA Levels in Human Muscle PLOS ONE , Dec 2019 Johann Edge , Toby Mündel , Henriette Pilegaard , Emma Hawke , Murray Leikis , Nicolas Lopez-Villalobos , Rodrigo S. F. Oliveira , David J. Bishop Benzalkonium chloride (BAK), otherwise known as alkyl dimethyl benzyl ammonium chloride, is a toxic chemical used in cosmetics. Gives off irritating or toxic fumes (or gases) in a fire. First Aid Procedures: Inhalation: Move to fresh air. Explosion: Not considered to be an explosion hazard. Do not take 2 doses at the same time or extra doses. Benzalkonium chloride (BZK, BKC, BAK, BAC), also known as alkyldimethylbenzylammonium chloride (ADBAC) and by the trade name Zephiran, is a type of cationic surfactant.It is an organic salt classified as a quaternary ammonium compound.ADBACs have three main categories of use: as a biocide, a cationic surfactant, and a phase transfer agent. Mixtures of about 16% to 25% (by volume) ammonia gas in air are flammable. Note to physician: Symptoms : Overexposure may cause:, vomiting, lethargy, confusion, hyperventilation, nausea, headache. When heated to decomposition this chemical emits very toxic fumes of carbon monoxide, carbon dioxide, nitrogen oxides and hydrogen chloride gas. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. The control group contained 20 animals and the test group contained 10 animals. Didecyl dimethyl ammonium chloride is registered for these antimicrobial uses by the U.S. EPA Office of Pesticide Programs. 103 is the average normal serum chloride concentration (mEq/L) and 0.2 L/kg is the estimated chloride volume of distribution. cause serious harm. Fire-fighting measures. We present a case of an intentional ingestion of a dilute ammonium chloride solution resulting in significant morbidity. Alkyl* dimethyl benzyl ammonium chloride *(58%C14, 28%C16, 14%C12) - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information: Note: See Working with the Information on this Page section below for important notes about this data. Ingestion: Harmful if swallowed. Chloride content— Transfer an accurately measured volume of Injection, evaporated, if necessary, equivalent to about 2 g of ammonium chloride, to a 200-mL volumetric flask, dilute with water to volume, and mix. Ammonium hydroxide can also release ammonia gas into the air. Sources/Uses. A 60-year-old woman with bipolar disorder presented one hour after an intentional ingestion of approximately 15 fluid ounces (500 mL) of an algae and odor humidifier treatment containing a total of 2.25% ethyl ammonium chloride. Water spray may Ammonium chloride fume may cause an asthma-like allergy. Other CAS RN: 8001-54-5; Other UN numbers are possible, depending on manufacturers´classifications. Acidic inorganic salts, such as ZINC AMMONIUM CHLORIDE, are generally soluble in water. Ingestion can cause irritation or corrosion of the alimentary tract. Ammonium chloride ingestion attenuates exercise-induced mRNA levels in human muscle Research output : Contribution to journal › Journal article › Research › peer-review Presentation No Results . Use … Ammonia is manufactured by reacting hydrogen with nitrogen. This website and underlying databases are maintained and updated by Pesticide Action Network North America (PAN). Materials and methods. It is also harmful by inhalation or skin absorption. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Inhalation of ammonium chloride fumes can result in irritation of the nose, throat and lungs, including coughing and a sore throat. Healthy young adult male subjects (n = 8) completed both a control (CON) and NH 4 Cl ingestion (ACID) trial.Phosphorus-31 magnetic resonance spectroscopy was used to monitor changes … ACUTE/CHRONIC HAZARDS: This compound is highly toxic by ingestion. It is also used as a refrigerant gas, and in the manufacture … This study examined the effects of NH 4 Cl ingestion on phosphocreatine (PCr) metabolism during 9 min of moderate- (MOD) and heavy- (HVY) intensity constant-load isotonic plantar-flexion exercise. At fire temperatures ammonium chloride begins to corrode metals and may dissociate into ammonia and hydrogen chloride. When didecyl dimethyl ammonium chloride is released to the environment, it will absorb to surfaces. Ammonium chloride ingestion attenuates exercise-induced mRNA levels in human muscle Edge, Johann; Muendel, Toby; Pilegaard, Henriette; Hawke, Emma; Leikis, Murray; Lopez- People with impaired respiratory functions, such as those with emphysema much incur further damage if the chemical is inhaled. Therefore, before using this … If not breathing, give artificial respiration. mEq of chloride ion (as ammonium chloride-NH4Cl) = [0.2 L/kg X BW (kg)] X [103 - observed serum chloride]; administer 50% of dose over 12 hr and reevaluate. (NTP, 1992) Reactivity Profile. Ammonium Chloride Safety Data Sheet according to Federal Register / Vol. Call a physician if symptoms occur. 58 / Monday, March 26, 2012 / Rules and Regulations Issue date: 07/24/2006 Revision date: 05/21/2020 Supersedes: 11/02/2016 Version: 2.2 05/21/2020 EN (English US) Page 1 SECTION 1: Identification . SIDS Initial Assessment Report For SIAM 17 - Ammonium Chloride (12125-02-9) Author: OECD SIDS Year: 2004 Bibliographic source: OECD- submitted on Janaury 30th 2004. Interaction Checker. May cause systemic toxicity with acidosis. Effect of sodium bicarbonate and ammonium chloride ingestion in experimental gentamicin nephrotoxicity in rats. The EU classification refers to a group of substances known as quaternary ammonium compounds, benzyl C8-18-alkyldimethyl chlorides. Ingestion. Abstract. Ingestion of ammonium hydroxide, while uncommon, results in corrosive damage to the mouth, throat, and stomach. Participants ingested either ammonium chloride (0.15 g.kg-1, ACID) or placebo (0.15 g.kg-1, PLA) in four doses during the 24 h prior to the trial day. Fire Extinguishing Media: Use any means suitable for extinguishing surrounding fire. 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